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|Drug||8th Grade||10th Grade||12th Grade|
|DRUG||PHYSICAL EFFECT OF MISUSE (SUBACUTE)||TOXIC EFFECT (ACUTE)||WITHDRAWAL (NONACUTE)||LABORATORY TESTING|
|Opioids||Euphoria, sedation, constipation, ulcers, respiratory depression||Depression, miosis, pulmonary edema, hypotension, respiratory arrest||Restlessness, insomnia, tremors, twitching, lacrimation, skin flushing, diaphoresis, nausea, vomiting, tachycardia, hypertension, fever||Can be detected for several days after last use|
|Stimulants and Amphetamines||Euphoria, self-confidence, excitement, agitation, impaired judgment, increased concentration and alertness, psychosis, delirium, mania, anxiety, paranoia, confusion, hallucinations, weight loss, hypertension, insomnia, tachycardia or bradycardia, dilated pupils, chills, nausea/vomiting, chest pain, cardiac dysrhythmias||Restlessness, insomnia, tremors, seizure, coma, mood irritability, diaphoresis, risk for intracranial hemorrhage, palpitations, dry mouth, chest pain, hyperthermia, diastolic hypertension, hypertensive crisis, dysrhythmia including ventricular tachycardia, diarrhea, painful rashes||Mood swings, depression, suicidal ideations, increased appetite, drug craving, exhaustion, increased sleeping, vivid dreams||Detected in urine three hours to three days following ingestion|
|Tranquilizers||Drowsiness, ataxia, dizziness, memory impairment, psychomotor changes, paradoxical reaction of agitation||Often occurs with co-consumption of alcohol; sedation, dysarthria, nystagmus, blurred vision, paresthesia||Insomnia, hypersensitivity to light and sound, irritability, twitching, confusion, delirium, seizures, tachycardia||Can be detected in urine several weeks following ingestion|
|Sedatives||Slurred speech, unsteady gait, impaired judgment and agitation, disinhibited behaviors, drowsiness, dizziness, confusion, blurred vision, amnesia||Nystagmus, ataxia, confusion, emotional lability, decreased corneal reflexes, unresponsiveness or coma, respiratory depression, poor temperature regulation||Restlessness, tremors, hyperactive reflexes, insomnia, anxiety, hallucinations, delirium, cramps, seizures, nausea, vomiting||Detected in both urine and serum testing|